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. Author manuscript; available in PMC: 2010 Jan 1.
Published in final edited form as: Pharmacol Biochem Behav. 2008 Sep 8;91(3):453–460. doi: 10.1016/j.pbb.2008.08.028

Figure 1.

Figure 1

Fear memory impairing effects of Ro 25-6981 on multi-trial, one-trial and low-lock shock fear conditioning. (A) Schematic of the multi-trial high shock protocol. (B) Pre-training treatment with 10 mg/kg Ro 25-6981 reduced fear recall relative to vehicle (0) (n=16–18/dose). (C) Schematic of the one-trial high-shock conditioning protocol. (D) Pre-training treatment with 10 mg/kg Ro 25-6981 reduced fear recall relative to vehicle (0) (n=13–14/dose). (E) Schematic of multi-trial low-shock protocol. (F) Pre-training treatment with 10 mg/kg Ro 25-6981 reduced fear recall relative to vehicle (0) (n=15–16/dose). **p<.01, *p<.05 vs. vehicle (0). Data in Figures 1–4 are Means ±SEM.