Table 2.

Response to Treatment

Response	150 PRE (n = 28)	1,500 PRE (n = 29)	1,500 POST (n = 29)
Median No. of cycles	4	4	4
No. of responders	5	10	8
Response rate, %	18	34	28
95% CI	6 to 37	18 to 54	13 to 47
Overall survival, months
Median	10	15	10
95% CI	8 to 16	8 to NR	5 to 16
1-year survival rate, %	49	63	48
2-year survival rate, %	25	42	26
Time to progression, months
Median	4	4	5
95% CI	3 to 5	3 to 6	3 to 8

Abbreviations: 150 PRE, erlotinib 150 mg on days 1 and 2 followed by chemotherapy on day 3; 1,500 PRE, erlotinib 1,500 mg on days 1 and 2 followed by chemotherapy on day 3; 1,500 POST, chemotherapy on day 1 followed by erlotinib 1,500 mg on days 2 and 3; NR, not reached.