TABLE 4.
Results of Proportional Hazards Analyses Relating Clinical Characteristics to Mortality Among Men and Women With PAD*
| Covariates | Hazard Ratios (95% CI) | P |
|---|---|---|
| Age (per year) | 1.01 (0.98–1.05) | 0.560 |
| Male gender | 1.23 (0.57–2.67) | 0.604 |
| Black | 1.52 (0.76–3.06) | 0.236 |
| BMI (kg/m2) | 0.95 (0.89–1.01) | 0.112 |
| Diabetes mellitus | 2.50 (1.40–4.45) | 0.002 |
| HDL cholesterol (mg/dL) | 0.98 (0.96–1.00) | 0.104 |
| Total cholesterol (mg/dL) | 1.01 (1.00–1.02) | 0.082 |
| Hypertension | 2.18 (0.88–5.42) | 0.092 |
| No. of cardiovascular diseases | 1.24 (0.95–1.62) | 0.108 |
| Cigarette smoking (pack-years) | 1.00 (0.99–1.01) | 0.704 |
| ABI | 2.89 (0.42–20.18) | 0.284 |
| History of coronary revascularization | 0.61 (0.31–1.17) | 0.137 |
| Pulmonary disease | 1.95 (1.05–3.63) | 0.035 |
| Cancer | 1.60 (0.78–3.26) | 0.199 |
| Leg symptoms | ||
| No exertional pain | 0.36 (0.11–1.15) | 0.083 |
| Pain relieved with rest | 0.65 (0.19–2.18) | 0.481 |
| Intermittent claudication | 0.63 (0.20–1.95) | 0.420 |
| Pain at rest | 0.59 (0.20–1.77) | 0.349 |
| Physical activity | ||
| 4th quartile of physical activity (≥1113 activity units) | 1.0 (Referent) | N/A |
| 3rd quartile of physical activity (788 to <1113 activity units) | 1.34 (0.43–3.18) | 0.609 |
| 2nd quartile of physical activity (540 to<788 activity units) | 2.66 (0.92–7.67) | 0.070 |
| 1st quartile of physical activity (<540 activity units) | 3.48 (1.23–9.87) | 0.019 |
*
Results of multivariable Cox model including variables listed in Table. Model corresponds to analyses presented in Figure 1.