Table 2. Odds Ratios for Glomerular Filtration Rate (GFR) Less than 60 mL/min, According to Age Group, Sex, and Body Mass Index (BMI) Status in a Population of People Aged 65 and Older with Normal Serum Creatinine Values.
GFR Estimation with Cockcroft-Gault Equation | GFR Estimation with Creatinine Clearance Calculated Using 24-Hour Urine Collection | |||||
---|---|---|---|---|---|---|
Characteristic | Cases/Total (%) | OR (95% CI) | P-value | Cases/Total (%) | OR (95% CI) | P-value |
Age | ||||||
65–74 | 71/381 (18.6) | 1.00* | 57/381 (15.0) | 1.00* | ||
75–84 | 126/216 (58.3) | 10.32 (6.36–16.75) | <.001 | 77/216 (35.7) | 3.25 (2.14–4.93) | <.001 |
≥85 | 61/63 (96.8) | 216.15 (48.80–957.50)† | <.001 | 37/63 (58.7) | 7.48 (4.05–13.8)† | <.001 |
Sex | ||||||
Male | 95/302 (31.5) | 1.00* | 51/302 (16.9) | 1.00* | ||
Female | 163/358 (45.5) | 3.13 (1.97–4.96) | <.001 | 120/358 (33.5) | 2.90 (1.92–4.39) | <.001 |
BMI, kg/m2 | ||||||
<22.0 | 38/47 (80.9) | 15.66 (6.40–38.28) | <.001 | 26/47 (55.3) | 4.20 (2.10–8.44) | <.001 |
22.0–24.9 | 99/141 (70.2) | 7.05 (4.05–12.26) | <.001 | 52/141 (36.9) | 1.85 (1.15–2.97) | .01 |
25.0–29.9 | 98/302 (34.5) | 1.00* | 67/302 (22.2) | 1.00* | ||
≥30.0 | 23/170 (13.5) | 0.22 (0.11–0.40)† | <.001 | 26/170 (15.3) | 0.58 (0.34–0.98)† | .04 |
Reference group.
P<.001 for trend.
OR = odds ratio; CI = confidence interval.