Table 1.
Characteristic | 1st Quartile (<22 μg/dL) N = 163 | 2nd Quartile (22–40 μg/dL) N = 147 | 3rd Quartile (40–68 μg/dL) N = 145 | 4th Quartile (>68 μg/dL) N = 84 | p Value* |
---|---|---|---|---|---|
Age, y† | 80.0 (7.6) | 76.9 (7.5) | 77.0 (8.1) | 75.4 (7.6) | <.001 |
Black, % | 19.0 | 30.6 | 29.7 | 40.5 | <.01 |
Education, y | 9.9 | 9.6 | 9.8 | 9.4 | .73 |
Current smoking status, % | 9.2 | 12.2 | 12.4 | 15.5 | .53 |
Body mass index, kg/m2 | 27.7 | 28.7 | 29.0 | 29.8 | .13 |
Oral estrogen use, % | 12.9 | 6.8 | 4.1 | 4.8 | .02 |
Oral corticosteroid use, % | 11.7 | 2.0 | 2.1 | 1.2 | <.001 |
Natural menopause, % | 65.5 | 65.3 | 66.2 | 60.7 | .85 |
Bilateral oophorectomy, % | 20.0 | 18.6 | 19.0 | 19.5 | .99 |
Chronic diseases, % | |||||
Osteoarthritis | 46.6 | 56.5 | 47.6 | 50.0 | .32 |
Coronary heart disease | 38.0 | 35.4 | 29.0 | 21.4 | .04 |
Chronic obstructive pulmonary disease | 31.3 | 32.0 | 24.8 | 25.0 | .40 |
Peripheral arterial disease | 22.1 | 24.5 | 17.2 | 14.3 | .20 |
Diabetes mellitus | 18.4 | 15.7 | 18.6 | 15.5 | .85 |
Congestive heart failure | 12.9 | 10.2 | 11.7 | 3.6 | .14 |
Cancer | 10.4 | 10.9 | 9.0 | 16.7 | .34 |
Stroke | 7.4 | 6.8 | 4.1 | 4.8 | .61 |
Rheumatoid arthritis | 6.8 | 0.7 | 2.8 | 1.2 | .01 |
Hip fracture | 6.1 | 6.8 | 9.0 | 2.4 | .28 |
Activities of daily living, %‡ | .95 | ||||
0 | 35.0 | 36.1 | 35.9 | 40.5 | |
1 | 28.8 | 29.3 | 29.7 | 25.0 | |
2 | 12.9 | 15.0 | 13.1 | 17.9 | |
≥3 | 23.3 | 19.7 | 21.4 | 16.7 |
Notes: Multiply by .02714 to convert from conventional (μg/dL) to SI units (μmol/L).
Based on analysis of variance test for continuous outcomes and chi-square test for categorical outcomes.
Expressed as mean (standard deviation).
Number of activities of daily living tasks (bathing, getting in/out of bed, using toilet, dressing, eating) with any difficulty.
DHEAS = dehydroepiandrosterone sulfate; WHAS I = Women’s Health and Aging Study I.