. Author manuscript; available in PMC: 2009 Feb 20.

Published in final edited form as: Proteomics Clin Appl. 2008 Oct 10;2(12):1575–1585. doi: 10.1002/prca.200780095

Table 4.

Discriminant Vector from MANOVA on All 19 Serum Factors^a)

Serum factors	Vector coefficients^b)	Factor r² with discriminant vector
IL-8	0.4708
HGF	−0.4460
MIG	0.3413
IL-12p40	−0.3399
IL-5	−0.3170
IP-10	−0.2206
IL-6	0.2138
TNF-RII	0.2008
MIP-1a	−0.2008
RANTES	0.1929
EOTAXIN	−0.0909
IL-1a	−0.0883
TNFa	−0.0737
TNF-RI	0.0700
IL-4	−0.0653
IL-15	0.0422
IL-13	−0.0324
G-CSF	0.0316
EGF	−0.0129

^a)

Factors were transformed to log₂, and standardized to zero mean and unit variance for extraction of discriminant vector via MANOVA.

^b)

The discriminant vector is normalized to length = 1.00, and points in direction of maximum separation between Benign and Malignant groups.

^c)

Factor r² with discriminant vector are calculated as the squares of the vector coefficients, and add up to 100%. The five factors in the first group (r²s>10%; bold text) account for 75.5% of the total r² with the gradient of separation between groups.