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. 2009 Mar 6;5(3):e1000297. doi: 10.1371/journal.pcbi.1000297

Table 1. Robustness as a function of the mode of EIpI formation.

Mode of EIpI Formation Robustness of [I]
Random order Yes
Ordered, with Ip binding E and EIp binding I Yes
Ordered, with I binding E and EI binding Ip No

In all cases, the ternary complex is assumed to have more kinase than phosphatase activity, Inline graphic, and Inline graphic.