Table 2. Clinical data of preterm infants.
Healthy preterm | Bronchopulmonary dysplasia | |||
mild | moderate | severe | ||
Number of subjects | 58 | 44 | 53 | 30 |
Prenatal steroids1 | 44 (76) | 36 (86) | 46 (88) | 24 (86) |
Chorioamnionitis2 | 9 (16) | 25 (57) | 20 (38) | 11 (41) |
Prenatal smoking | 1 of 52 (2) | 8 of 41 (20) | 8 of 45 (18) | 3 of 22 (14) |
Endotracheal intubation | 22 (38) | 28 (64) | 40 (75) | 22 (73) |
Continuous positive airway pressure (CPAP) | 42 (72) | 43 (98) | 52 (98) | 30 (100) |
APGAR 5 min | 8.4+1.2 (5–10) | 7.7+1.4 (2–10) | 6.8+1.7 (2–9) | 7.4+2.1 (3–10) |
APGAR 10 min | 8.9+1.0 (5–10) | 8.3+1.0 (5–10) | 7.7+1.5 (3–9) | 8.6+1.3 (6–10) |
Days of supplementary oxygen3 | 8+7 (0–27) | 46+13 (28–72) | 78+29 (3–200) | 144+108 (33–508) |
CRIB Score4 | 1.4+1.8 (0–9) | 4.1+3.1 (0–12) | 5.3+4.0 (1–14) | 6.0+3.3 (1–13) |
Data is given as number (percentage) or mean+/−SD (range).
Prenatal steroids if given parenterally before delivery.
Diagnosis of maternal chorioamnionitis was made by postnatal histopathological examination of the placenta.
All infants were off oxygen at time of analysis.
CRIB Score is a postnatal score including birthweight, gestational age, minimum and maximum FiO2 and maximum Base Excess during the first 12 hours as well as malformations. It can range from minimum 0 points to maximum 23 [26].