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. Author manuscript; available in PMC: 2009 Mar 1.
Published in final edited form as: Clin Chem. 2008 Jan 17;54(3):475–481. doi: 10.1373/clinchem.2007.095521

Table 1. Characteristics of the study population according to creatinine clearance strata.

Creatinine clearance

<30 mL/min 30–59 mL/min >60 mL/min Pa
n 27 383 521
Age, years 87.50 (5.00) 79.65 (7.34) 71.87 (4.68) <0.0001
Female, % 70.4 65.8 47.22 <0.0001
Education, years 4 (3–5) 5 (3–5) 5 (5–6) 0.26
Current smokers, % 15 12.4 24.6 0.0002
Former smokers, % 29 24.3 37.9 0.0002
Smoking, pack-years 0.0 (0.0–25.4) 0.0 (0.0–8.2) 0.0 (0.0–28.0) 0.47
Alcohol, g/day 10.0 (7.14–28.57) 10.0 (4.29–20.0) 13.57 (5.71–22.86) 0.20
MMSE score 18.74 (8.20) 23.31 (5.15) 25.66 (3.59) 0.13
BMI, kg/m2 24.38 (4.00) 25.77 (3.68) 28.59 (3.76) <0.0001
Energy intake, kcal/day 1535 (344.29) 1813.65 (542.70) 2017.69 (562.32) 0.90
Carbohydrate intake, g/day 202.83 (44.84) 237.28 (76.08) 259.96 (82.28) 0.593
Protein intake, g/day 59.80 (15.29) 71.73 (20.50) 78.53 (19.76) 0.32
Total lipid intake, g/day 50.99 (14.46) 61.13 (20.26) 67.48 (19.31) 0.75
Saturated FA intake, g/day 17.68 (5.48) 21.15 (8.03) 22.47 (7.69) 0.44
Monounsatured FA intake, g/day 24.81 (7.91) 30.12 (10.55) 34.14 (10.77) 0.78
Polynsaturated FA intake, g/day 5.72 (1.70) 6.60 (2.11) 7.43 (2.21) 0.79
Total cholesterol, mg/L 2004.1 (277.0) 2161.2 (425.0) 2169.5 (390.8) 0.18
LDL cholesterol, mg/L 1168.9 (212.4) 1340.1 (358.0) 1369.7 (341.1) 0.07
HDL cholesterol, mg/L 487.0 (159.2) 584.3 (169.7) 544.7 (135.1) 0.02
Triglycerides, mg/L 1734.4 (989.2) 1185.1 (535.5) 1275.6 (685.0) 0.0004
Total plasma PUFAs, mg/L 32.26 (4.80) 37.34 (4.87) 37.76 (4.85) <0.0001
Plasma n-3 FA, mg/L 2.69 (0.58) 3.34 (0.97) 3.29 (0.96) 0.004
Plasma n-6 FA, mg*10/L 2.76 (0.45) 3.26 (0.44) 3.24 (0.45) <0.0001
CRP, mg/L 4.66 (1.76–15.20) 2.59 (1.30–5.56) 2.89 (1.36–5.85) <0.0001
Urine protein, mg/L 0 (0–5) 0.0 (0.0–0.0) 0.0 (0.0–0.0) 0.04
Coronary heart disease, % 10.00 5.93 5.21 0.43
Stroke, % 15.38 6.70 4.12 0.01
Diabetes, % 11.11 10.98 11.89 0.67
Hypertension, % 60.00 48.52 17.28 0.38
Peripheral artery disease, % 20.00 8.09 4.98 0.004
Congestive heart failure, % 44.44 8.56 4.86 <0.0001
COPD, % 26.92 7.18 8.65 0.35
Cancer, % 11.11 6.79 5.79 0.30

Continuous variables expressed as mean (SD) or as median (IQR).

a

From age-, sex-, and BMI-adjusted linear or multinomial logistic regression models as appropriate.