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. Author manuscript; available in PMC: 2009 Mar 1.
Published in final edited form as: Clin Chem. 2008 Jan 17;54(3):475–481. doi: 10.1373/clinchem.2007.095521

Table 4. Odds of developing renal insufficiency (n = 134) (defined by a creatinine clearance <60 mL/min, among the 398 participants with creatinine clearance >60 mL/min at baseline) over 3-year follow-up according to plasma baseline PUFA level.

Crude odds ratio (95% CI) P Fully adjusted odds ratio (95% CI)a P
Total plasma PUFAs, mg/L 0.95 (0.91–0.99) 0.02 0.94 (0.89–0.99 0.015
Plasma n-3 FA, mg/L 0.60 (0.35–1.04) 0.06 0.68 (0.37–1.28) 0.23
Plasma linolenic acid, mg/L 0.98 (0.96–1.01) 0.10 0.99 (0.96–1.01) 0.30
Plasma n-6 FA, mg*10/L 0.68 (0.42–1.10) 0.11 0.96 (0.88–1.00) 0.09
Plasma linoleic acid, mg*10/L 0.99 (0.98–1.01) 0.59 1.00 (0.98–1.02) 0.98
Plasma arachidonic acid, mg*10/L 0.99 (0.96–1.02) 0.44 0.98 (0.96–1.02) 0.49
a

Adjusted for education, cigarette smoking pack-years, MMSE score, energy intake, alcohol, LDL cholesterol, HDL cholesterol, cancer, congestive heart failure, cardiovascular disease, and hypertension.