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. Author manuscript; available in PMC: 2009 Mar 1.
Published in final edited form as: Clin Chem. 2008 Jan 17;54(3):475–481. doi: 10.1373/clinchem.2007.095521

Table 5. Odds of developing renal insufficiency (defined by a creatinine clearance <60 mL/min, among the 398 participants with creatinine clearance >60 mL/min at baseline) or dying over 3-year follow-up according to plasma baseline PUFA level.

Crude odds ratio (95% CI) P Fully adjusted odds ratio (95% CI)a P
Total plasma PUFAs, mg/L 0.95 (0.91–0.99) 0.02 0.98 (0.94–1.03) 0.36
Plasma n-3 FA, mg/L 0.47 (0.30–0.74) 0.001 0.53 (0.31–0.88) 0.02
Plasma linolenic acid, mg/L 0.96 (0.95–0.98) 0.002 0.97 (0.95–0.99) 0.008
Plasma n-6 FA, mg*10/L 0.71 (0.48–1.05) 0.08 0.93 (0.57–1.54) 0.19
Plasma linoleic acid, mg*10/L 0.98 (0.97–0.99) 0.01 0.99 (0.98–1.01) 0.30
Plasma arachidonic acid, mg*10/L 0.98 (0.96–1.01) 0.07 0.98 (0.95–1.01) 0.16
a

Adjusted for education, cigarette smoking pack-years, MMSE score, energy intake, alcohol, LDL cholesterol, HDL cholesterol, cancer, congestive heart failure, cardiovascular disease, and hypertension.