Table 1.
Description of genetic variation surveyed in a 30 Mb region on chromosome 10
| Gene | Gene Name | SNP ID | Location (Mb) |
Allele Frequency |
|---|---|---|---|---|
| MYO3A | Myosin IIIA | rs7911700 | 26.326372 | 0.60 (G)/0.40 (A) |
| GAD2 | Glutamate decarboxylase 2 | rs8190612 | 26.552381 | 0.87 (G)/0.13 (A) |
| APBB1IP | Amyloid beta (A4) precursor protein-binding | rs1932253 | 26.769118 | 0.67 (A)/0.33 (G) |
| TRPT | Trans-prenyltransferase | rs1748354 | 27.033395 | 0.58 (T)/0.42 (A) |
| SSH3BP1 | Abl-interactor 1 | rs6482575 rs2018904 rs2505963 rs2505956 |
27.110610 27.121908 27.200938 27.225292 |
0.56 (C)/0.44 (G) 0.82 (T)/0.18 (C) 0.62 (G)/0.38 (A) 0.74 (C)/0.26 (T) |
| YME1L1 | YME1-like 1 | rs9833 rs11015538 |
27.440867 27.441062 |
0.84 (G)/0.16 (A) 0.81 (A)/0.19 (G) |
| MASTL | Microtubule associated serine/threonine kinase-like | rs2274636 | 27.483018 | 0.88 (T)/0.12 (C) |
| RAB18 | Member RAS oncogene family | rs2477343 | 27.842426 | 0.63 (A)/0.37 (G) |
| WAC | WW domain containing adaptor with coiled-coil | rs332136 | 28.898584 | 0.54 (T)/0.46 (C) |
| BAMBI | BMP and activin membrane-bound inhibitor homolog | rs1888085 rs675558 |
29.006500 29.008312 | 0.88 (T)/0.12 (G) 0.61 (G)/0.39 (A) |
| SVIL | Supervillin isoform 2 | rs1886999 | 29.790956 | 0.52 (A)/0.48 (G) |
| MAP3K8 | Mitogen-activated protein kinase kinase kinase 8 | rs306588 rs1042058 rs3034 |
30.763599 30.768107 30.789901 |
0.74 (A)/0.26 (G) 0.60 (C)/0.40 (T) 0.87 (T)/0.13 (C) |
| TCF8 | Transcription factor expression 8 | rs3758455 | 31.655255 | 0.92 (G)/0.08 (A) |
| ARHGAP12 | Rho GTPase activating protein 12 | rs2255555 rs2808074 |
32.154956 32.219190 |
0.79 (A)/0.21 (G) 0.51 (C)/0.49 (A) |
| KIF5B | Kinesin family member 5B | rs2286746 | 32.348400 | 0.91 (T)/0.09 (G) |
| EPC1 | Enhancer of polycomb homolog 1 | rs11592754 | 32.659578 | 0.88 (T)/0.12 (G) |
| ITGB1 | Integrin, beta 1 | rs1187072 | 33.283813 | 0.53 (T)/0.47 (A) |
| NRP1 | Neuropilin 1 | rs1888690 rs2804495 |
33.575802 33.652506 |
0.86 (G)/0.14 (C) 0.70 (T)/0.30 (G) |
| PARD3 | PAR-3 partitioning defective 3 homolog | rs3781128 rs1657224 |
34.660226 34.877634 |
0.52 (C)/0.48 (T) 0.57 (T)/0.43 (A) |
| CUL2 | Cullin2 | rs12240347 | 35.399481 | 0.67 (A)/0.33 (G) |
| CREM | cAMP responsive element modulator | rs1148247 | 35.536952 | 0.56 (C)/0.44 (T) |
| CFP1 | Cyclin fold protein 1 | rs11010188 rs1362999 |
35.718856 35.792555 |
0.71 (A)/0.29 (G) 0.58 (T)/0.42 (A) |
| NYBR1 | Breast cancer antigen | cv26944508 | NA | 0.53 (C)/0.47 (A) |
| ZNF25 | Zinc finger protein 25 | rs13503 | 38.279849 | 0.53 (A)/0.47 (C) |
| ZNF33a | Zinc finger protein 33a | rs633400 | 38.369427 | 0.88 (G)/0.12 (C) |
| ZNF11B | Zinc finger protein 11B | rs209390 rs2473116 |
42.448886 42.456895 |
0.84 (G)/0.16 (A) 0.59 (G)/0.41 (A) |
| RET | Ret proto-oncogene | rs1800858 | 42.915974 | 0.73 (G)/0.27 (A) |
| GALNACT2 | Chondroitin sulfate | rs7092548 | 42.990811 | 0.82 (C)/0.18 (T) |
| FXYD4 | FXYD domain containing ion transport regulator 4 | rs10899795 | 43.189103 | 0.80 (C)/0.20 (A) |
| HNRPF | Heterogeneous nuclear ribonucleoprotein F | rs7905676 rs4597022 |
43.201081 43.205226 |
0.66 (T)/0.34 (C) 0.81 (C)/0.19 (G) |
| ZNF239 | Zinc finger protein 239 | rs2230660 rs3763789 |
43.373019 43.381366 |
0.92 (C)/0.08 (G) 0.89 (T)/0.11 (C) |
| ZNF32 | Zinc finger protein 32 | rs3814561 | 43.461915 | 0.75 (A)/0.25 (G) |
| CXCL12 | Chemokine (C-X-C motif) ligand 12 | rs2839696 | 44.186634 | 0.97 (G)/0.03 (A) |
| RASSF4 | Ras association (RalGDS/AF-6) domain family 4 | rs3829908 | 44.784106 | 0.77 (G)/0.23 (A) |
| DEPP | Decidual protein induced by progesterone | rs3740094 | 44.793323 | 0.85 (G)/0.15 (A) |
| ZNF22 | Zinc finger protein 22 | rs11494 | 44.820227 | 0.96 (T)/0.04 (C) |
| ALOX5 | Arachidonate 5-lipoxygenase | rs2291427 | 45.256230 | 0.66 (G)/0.34 (A) |
| CTGLF1 | Centaurin, gamma-like family, member 1 | rs35963845 | 45.494334 | 0.79 (G)/0.21 (A) |
| GDF2 | Growth/differentiation factor 2 | rs3781226 | 48.036264 | 0.99 (G)/0.01 (A) |
| GDF10 | Growth/differentiation factor 10 | rs1902725 | 48.056248 | 0.80 (C)/0.20 (T) |
| MAPK8 | Mitogen-activated protein kinase 8 | rs1919709 | 49.190009 | 0.75 (G)/0.25 (A) |
| ARHGAP22 | Rho GTPase activating protein 22 | rs3789320 rs7898936 rs1445151 rs1345107 |
49.325369 49.376645 49.419580 49.464487 |
0.53 (T)/0.47 (G) 0.92 (C)/0.08 (T) 0.54 (T)/0.46 (C) 0.82 (G)/0.18 (A) |
| ERCC6 | Excision repair cross-complementing rodent repair deficiency, complementation group 6 |
rs1917801 | 50.414312 | 0.91 (G)/0.09 (A) |
| SLC18A3 | Solute carrier family 18, member 3 | rs3729496 | 50.491197 | 0.78 (A)/0.22 (C) |
| CHAT | Choline acetyltransferase | rs1880676 | 50.494123 | 0.77 (G)/0.23 (A) |
| PARG | Poly (ADP-ribose) glycohydrolase | rs7067802 | 50.708303 | 0.67 (A)/0.33 (G) |
| MSMB | Microseminoprotein, beta | rs4630240 | 51.202534 | 0.59 (G)/0.41 (A) |
| NCOA4 | Nuclear receptor coactivator 4 | rs10761618 | 51.244612 | 0.72 (A)/0.28 (G) |
| ACF | Apobec-1 complementation factor | rs12570156 | 52.279014 | 0.68 (A)/0.32 (G) |
| CSTF2T | Cleavage stimulation factor, 3′ pre-RNA, subunit 2, 64kDa, tau variant |
rs11601 | 53.127130 | 0.81 (G)/0.19 (A) |
| PRKG1 | cGMP-dependent protein kinase 1, alpha isoenzyme | rs1937652 rs7917364 rs12356995 |
53.235324 53.283507 53.396390 |
0.69 (T)/0.31 (C) 0.81 (A)/0.19 (G) 0.75 (G)/0.25 (A) |
| DKK1 | Dickkopf homolog 1 | rs2241529 rs1569198 |
53.744763 53.746277 |
0.56 (G)/0.44 (A) 0.53 (A)/0.47 (G) |
| MBL2 | Mannose-binding lectin 2, soluble | rs930507 rs1838065 |
54.198272 54.199263 |
0.84 (C)/0.16 (G) 0.60 (A)/0.40 (G) |
| PCDH15 | Protocadherin 15 | rs4481935 rs9787578 rs978841 |
55.254249 55.561682 55.734720 |
0.54 (A)/0.46 (G) 0.75 (C)/0.25 (A) 0.63 (C)/0.37 (T) |