Table 3.
Gene | SNP ID | SBP | DBP | SLC | |
---|---|---|---|---|---|
p-value (proportion of phenotypic variance attributable to the SNP) |
LOD score for SLC at 55 cM* | ||||
TRPT | rs1748354 | NS | 0.03 (0.004) | NS | NA |
YME1L1 | rs9833 | NS | NS | 0.04 (0.004) | 1.93 |
ZNF239 | rs3763789 | 0.03 (0.005) | NS | NS | NA |
ERCC6 | rs1917801 | NS | NS | 0.02 (0.007) | 1.94 |
DKK1 | rs2241529 | 0.04 (0.006) | <0.01 (0.007) | NS | NA |
MBL2 | rs930507 | <0.01 (0.007) | NS | <0.01 (0.006) | 1.50 |
MBL2 | rs1838065 | 0.03 (0.009) | NS | 0.04 (0.007) | 0.80 |
Variance-components models for evaluating association were adjusted for age, gender and triglyceride levels.
NS=not significant (p>0.05); NA=not applicable; SBP=systolic blood pressure; DBP=diastolic blood pressure; SLC=sodium-lithium countertransport
LOD score is reported at 55 cM for a linkage analysis model for SLC that includes each individual SNP.