TABLE 1.
DNA and protein distribution in the subcellular fractions of CD4+ T cells retrovirally expressing C-terminal extended Foxp3
DNA and protein measurements are described under “Experimental Procedures.” N, nuclear extract; C, cytoplasmic extract; Chr, chromatin fraction; T, total extract.
| DNA | Protein | Protein/DNA | |
|---|---|---|---|
| % | % | mg/ml | |
| Chr | 73 ± 2 | 36 ± 3 | 2.8 ± 0.2 |
| N | 1 ± 1 | 12 ± 1 | >200 |
| C | 26 ± 1 | 52 ± 4 | 11.5 ± 1 |
| T | 100 | 100 | 5.1 ± 0.1 |