FIGURE 3.
The 5-kDa selenoprotein is derived from full-length mouse MsrB1. A, protein sequence of mouse MsrB1. The identified cleavage site between Gly75 and Asn76 in MsrB1 is shown by a caret. The detected peptide derived from V8 protease cleavage is shown in blue. B, structural model of mouse MsrB1. The zinc atom was modeled based on the location of known ligands (4 cysteine residues from two CXXC motifs) of this metal ion. Predicted protease cleavage site is marked by a red dot and highlighted by scissors.