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. 2009 Feb 19;338:b349. doi: 10.1136/bmj.b349

Table 3.

 Relative risk (95% confidence interval) of incident stroke by number of health behaviours in various adjusted models in men and women aged 40-79 without known stroke and myocardial infarction in EPIC-Norfolk 1993-2007, Cox regression model

Model* Health behaviour score P value
4 3 2 1 0
Model A
All 1.0 1.19 (0.92 to 1.54) 1.67 (1.29 to 2.16) 2.42 (1.81 to 3.23) 2.59 (1.50 to 4.50) <0.001
Men 1.0 1.12 (0.76 to 1.64) 1.45 (0.99 to 2.12) 2.04 (1.33 to 3.13) 1.77 (0.75 to 4.21) 0.003
Women 1.0 1.20 (0.85 to 1.70) 1.84 (1.30 to 2.60) 2.71 (1.84 to 4.02) 3.51 (1.72 to 7.16) <0.001
Model B
All 1.0 1.16 (0.89 to 1.50) 1.61 (1.25 to 2.09) 2.26 (1.69 to 3.02) 2.39 (1.38 to 4.15) <0.001
Men 1.0 1.05 (0.71 to 1.54) 1.36 (0.93 to 1.99) 1.85 (1.21 to 2.84) 1.50 (0.63 to 3.57) 0.01
Women 1.0 1.21 (0.85 to 1.71) 1.83 (1.29 to 2.59) 2.59 (1.74 to 3.84) 3.50 (1.71 to 7.13) <0.001
Model C
All 1.0 1.15 (0.89 to 1.49) 1.58 (1.22 to 2.05) 2.18 (1.63 to 2.92) 2.31 (1.33 to 4.02) <0.001
Men 1.0 1.04 (0.71 to 1.53) 1.33 (0.91 to 1.96) 1.79 (1.16 to 2.74) 1.45 (0.61 to 3.45) 0.019
Women 1.0 1.20 (0.85 to 1.70) 1.80 (1.27 to 2.56) 2.53 (1.70 to 3.77) 3.40 (1.66 to 6.96) <0.001
Model D
All 1.0 1.09 (0.84 to 1.42) 1.53 (1.18 to 1.98) 2.07 (1.54 to 2.79) 2.15 (1.22 to 3.80) <0.001
Men 1.0 1.00 (0.67 to 1.47) 1.28 (0.87 to 1.89) 1.69 (1.09 to 2.61) 1.46 (0.61 to 3.48) 0.034
Women 1.0 1.13 (0.80 to 1.61) 1.75 (1.23 to 2.49) 2.41 (1.61 to 3.60) 3.00 (1.41 to 6.37) <0.001

*Model A: adjusted by age and sex; model B additionally adjusted for BMI, systolic blood pressure, cholesterol concentration, aspirin use, and diabetes mellitus; model C additionally adjusted for social class; model D: excluding incident strokes occurring within first 2 years of follow-up.