Table 3.
Relative risk (95% confidence interval) of incident stroke by number of health behaviours in various adjusted models in men and women aged 40-79 without known stroke and myocardial infarction in EPIC-Norfolk 1993-2007, Cox regression model
| Model* | Health behaviour score | P value | ||||
|---|---|---|---|---|---|---|
| 4 | 3 | 2 | 1 | 0 | ||
| Model A | ||||||
| All | 1.0 | 1.19 (0.92 to 1.54) | 1.67 (1.29 to 2.16) | 2.42 (1.81 to 3.23) | 2.59 (1.50 to 4.50) | <0.001 |
| Men | 1.0 | 1.12 (0.76 to 1.64) | 1.45 (0.99 to 2.12) | 2.04 (1.33 to 3.13) | 1.77 (0.75 to 4.21) | 0.003 |
| Women | 1.0 | 1.20 (0.85 to 1.70) | 1.84 (1.30 to 2.60) | 2.71 (1.84 to 4.02) | 3.51 (1.72 to 7.16) | <0.001 |
| Model B | ||||||
| All | 1.0 | 1.16 (0.89 to 1.50) | 1.61 (1.25 to 2.09) | 2.26 (1.69 to 3.02) | 2.39 (1.38 to 4.15) | <0.001 |
| Men | 1.0 | 1.05 (0.71 to 1.54) | 1.36 (0.93 to 1.99) | 1.85 (1.21 to 2.84) | 1.50 (0.63 to 3.57) | 0.01 |
| Women | 1.0 | 1.21 (0.85 to 1.71) | 1.83 (1.29 to 2.59) | 2.59 (1.74 to 3.84) | 3.50 (1.71 to 7.13) | <0.001 |
| Model C | ||||||
| All | 1.0 | 1.15 (0.89 to 1.49) | 1.58 (1.22 to 2.05) | 2.18 (1.63 to 2.92) | 2.31 (1.33 to 4.02) | <0.001 |
| Men | 1.0 | 1.04 (0.71 to 1.53) | 1.33 (0.91 to 1.96) | 1.79 (1.16 to 2.74) | 1.45 (0.61 to 3.45) | 0.019 |
| Women | 1.0 | 1.20 (0.85 to 1.70) | 1.80 (1.27 to 2.56) | 2.53 (1.70 to 3.77) | 3.40 (1.66 to 6.96) | <0.001 |
| Model D | ||||||
| All | 1.0 | 1.09 (0.84 to 1.42) | 1.53 (1.18 to 1.98) | 2.07 (1.54 to 2.79) | 2.15 (1.22 to 3.80) | <0.001 |
| Men | 1.0 | 1.00 (0.67 to 1.47) | 1.28 (0.87 to 1.89) | 1.69 (1.09 to 2.61) | 1.46 (0.61 to 3.48) | 0.034 |
| Women | 1.0 | 1.13 (0.80 to 1.61) | 1.75 (1.23 to 2.49) | 2.41 (1.61 to 3.60) | 3.00 (1.41 to 6.37) | <0.001 |
*Model A: adjusted by age and sex; model B additionally adjusted for BMI, systolic blood pressure, cholesterol concentration, aspirin use, and diabetes mellitus; model C additionally adjusted for social class; model D: excluding incident strokes occurring within first 2 years of follow-up.