Table 1.
Year of Follow-Up | Age < 50 Years (n = 199)
|
Age 50-79 Years (n = 366)
|
Age 80+ Years (n = 84)
|
All Participants (N = 649)
|
||||
---|---|---|---|---|---|---|---|---|
No. of Participants | % | No. of Participants | % | No. of Participants | % | No. of Participants | % | |
Eligible at start of follow-up* | 196 | 100 | 354 | 100 | 81 | 100 | 631 | 100 |
Start of year 2 | 181 | 92 | 338 | 95 | 77 | 95 | 596 | 94 |
Start of year 3 | 164 | 84 | 308 | 87 | 65 | 80 | 537 | 85 |
Start of year 4 | 138 | 70 | 256 | 72 | 39 | 48 | 433 | 69 |
Start of year 5 | 133 | 68 | 238 | 67 | 34 | 42 | 405 | 64 |
End of year 5 | 119 | 61 | 219 | 62 | 24 | 30 | 362 | 57 |
Eighteen enrolled participants were found to be ineligible at start of follow-up because there was no unaffected comparison side and lymphedema could not be evaluated, including 17 participants who had simultaneous bilateral mastectomies at the reference date (histologic confirmation of breast cancer diagnosis) and one participant with a pre-existing size difference affecting the entire arm. Among the 631 remaining eligible study participants, an additional six participants recalled a size difference in their hand, lower arm, or upper arm that preceded their breast cancer diagnosis. Five of these six participants had pre-existing size differences in only one part. These pre-existing size differences were not used to calculate incidence of lymphedema, although these six women contributed to estimating incidence rates based on the parts of the arm that were the same at diagnosis.