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(A) Model of the Z ring. The Z ring is constructed from overlapping short protofilaments and averages 3 to 9 protofilaments in thickness, depending on the bacterial strain. (B) FtsZ is normally tethered to the membrane by FtsA. The Cterminal peptide (orange) of FtsZ binds FtsA, and FtsA binds the membrane by its amphipathic helix (purple). (C) In FtsZ-mts, the FtsA-binding peptide is replaced with yellow fluorescent protein (YFP) and an amphipathic helix.
