Skip to main content
. Author manuscript; available in PMC: 2009 Dec 1.
Published in final edited form as: Hepatology. 2008 Dec;48(6):1769–1778. doi: 10.1002/hep.22549

Figure 2. Phylogenetic tree comparing full length HCV amino acid sequences from 362 genotype 1a infected patients.

Figure 2

Viral strains carrying identical drug resistance mutations are marked with identical colors. Only two strains carrying the M423I mutation in NS5B are directly related (Arrows 1), whereas other mutations clustering together are more distant (Arrows 2 and 3), with the majority of drug resistance mutations spread across the entire tree, thus excluding a bias for resistance mutations due to closely related variants in a certain subpopulation of the cohort.