Table 1.
| |||
---|---|---|---|
Entry | C-terminal AA | Time (h) | Yield |
1 | Thr (2) | 2 | 79% (7) |
2 | Val (3) | 6 | 69% (8) |
3 | Ile (4) | 7 | 70% (9) |
4 | D-allo-Ile (5) | 6 | 60% (10) |
5 | Pro (6) | 15 | 50% (11) |
Reagents and conditions: (a) Buffer at pH= 6.3–6.5 (6.0 M Gn·HCl, 188.8 mM Na2HPO4, 7.2 mM p-NO2PhOH), TCEP, RT