Skip to main content
. Author manuscript; available in PMC: 2009 Nov 27.
Published in final edited form as: J Med Chem. 2008 Nov 27;51(22):7144–7153. doi: 10.1021/jm800675p

Figure 6.

Figure 6

Inactivation of alkyltransferase in HT29 cells. Panel A shows the loss of alkyltransferase (hAGT) activity as a function of time after addition of the compound indicated to cultures of HT29 cells. Panel B shows the effect of exposing HT29 cells to the compound indicated for 2 h prior to the addition of 40 μM BCNU. Cell survival was then measured using a colony forming assay as described in the Experimental Section.