Table 1.

Correlation of ET identified RGS residues with PDEγ effects

RGS protein	PDEγ effect*	ET identified residue number (based on the RGS4)
		77	117	121	122	124	126	134
RGS4†	Inhibit	Lys	Glu	Val	Gln	Thr	Glu	Arg
RGS16‡	Inhibit	His	Glu	Ser	Glu	Pro	Glu	Arg
GAIP†	Inhibit	Arg	Asp	Ile	Leu	Pro	Glu	Arg
RGS6§	Inhibit	Leu	Glu	Pro	Gly	Pro	Ala	Tyr
RGS9¶	Enhance	Gln	Leu	Pro	Gly	Arg	Trp	Met
RGS11§	None	Met	Gln	Pro	Gly	Ala	Trp	Met

*Effect of PDEγ on GAP activity. 

^†Ref. 14. 

^‡Ref. 13. 

^§This work. 

^¶Ref. 11.