TABLE 5.

Cofactors by the rs2289669 polymorphism

	GG	GA	AA
Sex (male)	18 (50)	22 (38)	7 (33)
Age (years)	75.3 ± 7.0	77.9 ± 6.5	75.6 ± 6.1
A1C level before start (%)	8.3 ± 0.9	8.3 ± 1.4	8.4 ± 1.1
Prescribed metformin dose (mg)	853 ± 476	662 ± 262	757 ± 320
Sulfonylurea use (%)	22 (61)	33 (57)	13 (62)
Change in sulfonylurea dose (DDD)*	−0.01 ± 0.53	−0.17 ± 0.61	−0.27 ± 0.52
Time from diabetes diagnosis (years)	5.5 ± 4.4	5.6 ± 4.8	4.7 ± 3.7
Estimated glomerular filtration rate (ml/min)	74 ± 19	68 ± 17	68 ± 14
BMI (kg/m2)	28.9 ± 3.9	28.1 ± 3.8	27.6 ± 3.2

Data are means ± SD or n (%).

^*P = 0.08 for trend. DDD, defined daily dose.