Fig. 1.
Activin-type II receptor B (ACVR2B) haplotype structure. The tagged polymorphism, rs2268757, is shaded. Haplotypes 1 and 4 were combined to form Haplotype Group 1 (Hap Group 1), while haplotypes 2, 3, and 5 were combined to form Hap Group 2 for the analysis of ACVR2B haplotype structure. *Frequency data from the Centre d'Etude du Polymorphisme Humain (CEPH) cohort within the International HapMap Project database.