Table 4.
Independent factors of trabecular and cortical bone mineral density in older men and women
| Dependent variable vBMDt |
Dependent variable vBMDc |
|||||||
|---|---|---|---|---|---|---|---|---|
| Men |
Women |
Men |
Women |
|||||
| b + SE | P | b + SE | P | b + SE | P | b + SE | P | |
| Age (years) | −0.08 ± 0.44 | 0.84 | −1.95 ± 0.45 | <0.0001 | −1.20 ± 0.70 | 0.09 | −1.28 ± 0.53 | 0.0156 |
| BMI (kg/m2) | 3.42 ± 0.88 | <0.0001 | 2.39 ± 0.65 | <0.0001 | 3.9 ± 1.3 | 0.0029 | ||
| CSMA (cm2) | 1.0 ± 0.3 | 0.0010 | ||||||
| Ankle extension strength (kg * 100) | 0.04 ± 0.01 | 0.0012 | 0.02 ± 0.01 | 0.094 | ||||
| Physical activity | ||||||||
| Sedentary | −32.7 ± 13.8 | 0.0182 | ||||||
| Light | 20.0 ± 9.4 | 0.0348 | ||||||
| Moderate/High | Reference | |||||||
| Creatinine clearance (ml/min) | 0.48 ± 0.20 | 0.0297 | 0.55 ± 0.27 | 0.042 | ||||
| Serum 25 (OH)-Vitamin D (nmol/l) | 20.1 ± 6.97 | 0.0042 | ||||||
| Serum PTH (pmol/l) | −22.5 ± 8.7 | 0.0098 | ||||||
| Bio-T (ng/dl) | 13.1 ± 2.4 | <0.0001 | 5.9 ± 2.4 | 0.013 | 26.1 ± 6.2 | <0.0001 | 9.74 ± 3.6 | 0.0074 |
| IL-1 beta (pg/ml) | −2.9 ± 0.92 | 0.0015 | ||||||
Parsimonious model obtained by backward selection method from initial models including all covariates reported in the table plus education, WHR, calcium intake, DHEAS, TNF-alpha.