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. Author manuscript; available in PMC: 2009 Mar 27.
Published in final edited form as: Nature. 2008 Mar 12;452(7186):492–496. doi: 10.1038/nature06736

Figure 2. SIRT6 associates with telomeric chromatin.

Figure 2

a, Western analysis of U2OS cells transduced with pBabe-Flag-SIRT6 or empty virus (pBabe) control. b, T-ChIP analysis with anti-Flag antibodies from the cells shown in a. c, T-ChIP assays in U2OS cells with antibodies specific for SIRT6,WRNor IgG negative control. d, T-ChIP assays with SIRT6 antibodies in S6KD cells or in control pSR IMR90 cells. In b–d, slot-blots are shown of telomere or Alu repeat sequences in ChIP and input DNA. Input loaded represents 5% (b, c) or 2.5% (d) of total.