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. Author manuscript; available in PMC: 2009 Sep 10.
Published in final edited form as: J Am Chem Soc. 2008 Aug 19;130(36):12148–12155. doi: 10.1021/ja803646t

Figure 1.

Figure 1

Hydrolysis reactions of (-)-cocaine and (+)-cocaine: (a) reactants and products of the reactions; (b) schematic representation of the first reaction step for (-)-cocaine hydrolysis catalyzed by a BChE mutant including A199S mutation.