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. 2009 Jan 10;373(9658):125–136. doi: 10.1016/S0140-6736(08)61766-3

Table 5.

Adjuvant radiotherapy received (within 3 months after surgery), nodes removed, nodal status, and external-beam radiotherapy (EBRT) received in node-positive patients by risk group defined according to ASTEC radiotherapy eligibility

Standard surgery (N=683)* Lymphadenectomy (N=686)*
Low-risk early-stage endometrial cancer
Total 330 (49%) 282 (42%)
Radiotherapy received
Yes 22 (7%) 24 (9%)
No 305 (93%) 257 (91%)
Unknown 3 1
External beam +/− brachytherapy 12 (4%) 9 (3%)
Brachytherapy only 10 (3%) 15 (5%)
Nodes removed
Yes 8 (2%) 255 (92%)
No 314 (98%) 22 (8%)
Unknown 8 5
Median number of nodes (range) 2 (1–3) 12 (1–59)
Nodal involvement
Yes (received EBRT) 1 (1) 6 (2)
No 7 249
Intermediate-risk and high-risk early-stage endometrial cancer
Total 243 (36%) 264 (39%)
Radiotherapy received
Yes 137 (56%) 138 (53%)
No 106 (44%) 124 (47%)
Unknown 0 2
External beam +/− brachytherapy 102 (42%) 98 (37%)
Brachytherapy only 35 (14%) 40 (15%)
Nodes removed
Yes 14 (6%) 244 (93%)
No 226 (94%) 17 (7%)
Unknown 3 3
Median number of nodes (range) 1 (1–16) 12 (1–51)
Nodal involvement
Yes (received EBRT) 4 (1) 21 (12)
No 10 233
Advanced endometrial cancer
Total 103 (15%) 124 (19%)
Radiotherapy received
Yes 62 (61%) 64 (53%)
No 40 (39%) 56 (47%)
Unknown 1 4
External beam +/− brachytherapy 55 (54%) 55 (46%)
Brachytherapy only 7 (7%) 8 (7%)
Nodes removed
Yes 10 (10%) 103 (85%)
No 91 (90%) 18 (15%)
Unknown 2 3
Median number of nodes 2 (1–6) 13 (1–38)
Nodal involvement
Yes (received EBRT) 4 (0) 25 (8)
No 6 78
Unknown, unable to classify risk group
Total 7 16
*

Excludes patients whose pathology details did not confirm endometrial cancer.