Table 3.
Table 3a. Decreased regional gray matter volumes in BPI relative to HC | |||||||||
---|---|---|---|---|---|---|---|---|---|
Region | CoordinatesA | k | |||||||
Decreased GMV in BPI | Side | x | y | z | T | z | Unc. | Cor. | PB |
A priori regions | |||||||||
PMRG | R | 12 | 14 | −21 | 3.54 | 3.34 | 19 | 10 | 0.038 |
L | −13 | 12 | −21 | 3.54 | 3.33 | 19 | 6 | 0.037 | |
Non-a priori regions | |||||||||
Parahippocampal gyrus (BA37) | L | −27 | −46 | −18 | 4.24 | 3.91 | 66 | 25 | 0.008 |
Putamen | L | −25 | −15 | 6 | 3.6 | 3.38 | 33 | 30 | 0.017 |
Table 3b. Differences in regional gray matter volumes between males and females | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|
Region | CoordinatesA | K | ||||||||
Male greater female | Side | x | y | z | T | z | Unc. | Cor. | PB | Cohen’s d |
Inferior frontal gyrus (BA47) | L | −25 | 16 | −8 | 4.30 | 3.95 | 30 | 10 | 0.005 | 1.20 |
Cuneus (BA18) | L | −1 | −102 | 12 | 4.23 | 3.89 | 392 | 30 | 0.01 | 1.18 |
Cuneus (BA18) | R | 24 | −75 | 17 | 3.89 | 3.63 | 11 | 41 | 0.027 | 1.09 |
Inferior frontal gyrus (BA45) | L | −36 | 24 | 3 | 3.84 | 3.58 | 144 | 9 | 0.007 | 1.08 |
Inferior frontal gyrus (BA47) | R | 29 | 20 | −3 | 3.66 | 3.42 | 105 | 9 | 0.029 | 1.03 |
Female greater Male | ||||||||||
Precuneus (BA7) | L | −3 | −48 | 54 | 4.03 | 3.74 | 336 | 57 | 0.016 | 1.13 |
Superior parietal lobule (BA7) | L | −29 | −63 | 44 | 3.99 | 3.70 | 84 | 32 | 0.017 | 1.12 |
Inferior frontal gyrus (BA11) | L | −25 | 35 | −21 | 3.82 | 3.57 | 203 | 6 | 0.019 | 1.07 |
Middle temporal gyrus (BA21) | L | −57 | 4 | −18 | 3.66 | 3.43 | 64 | 8 | 0.029 | 1.03 |
Talaraich and Tornoux (1998) coordinates;
P values corrected with small volume correction; GMV: gray matter volume; BPI: Bipolar Disorder, type I; PMRG: posteromedial rectal gyrus; k: number of voxels in the cluster for both uncorrected and corrected values
Talaraich and Tornoux (1998) coordinates;
P values corrected with small volume correction; k: number of voxels in the cluster for both uncorrected and corrected values