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. Author manuscript; available in PMC: 2009 Feb 23.
Published in final edited form as: Science. 2006 Dec 15;314(5806):1780–1783. doi: 10.1126/science.1133690

Fig. 3.

Fig. 3

Effect of expressing the type II allele for ROP18 in a type III strain background (CEP) on virulence in mice. Mice were infected intra-peritoneally with either CEPΔhxgprt complemented with HXGPRT alone (CEP*) or CEP parasites complemented with the type II allele for ROP18 along with 588 bp of upstream sequence (type III:ROP18II). Infections were verified in all the survivors based on the presence of Toxoplasma-specific antibodies, and only seropositive survivors are represented on the graph. Ten mice were used for all strain and dose combinations except for type III:ROP18II-100 (eight mice) and type III:ROP18II-10 (seven mice).