TABLE 3.

Prevalence of moderate hyperhomocysteinemia in MTHFR 677T homozygotes based on serum folate concentrations in a population of 844 Caucasian and 587 African American participants in the CARDIA study

	y 0, 1985		y 7, 1992		y 15, 2000
Range of folate, nmol/L	677 TT	tHcy >13 μmol/L	677 TT	tHCY >13 μmol/L	677 TT	tHcy >13 μmol/L
Caucasian	n	n (%)	n	n (%)	n	n (%)
<6.8	41	27 (65.9)	26	12 (46.2)	3	2 (66.7)
6.8–15.4	38	11 (28.9)	36	14 (38.9)	13	4 (30.8)
>15.4	35	1 (2.9)	52	3 (5.8)	98	6 (6.1)
Total	114	39 (34.2)	114	29 (25.4)	114	12 (10.5)
African Americans
<6.8	4	1 (25)	4	3 (75)	0	0 (0)
6.8–15.4	2	0 (0)	2	1 (50)	1	1 (100)
>15.4	1	0 (0)	1	0 (0)	6	1 (16.7)
Total	7	1 (14.3)	7	4 (57.1)	7	2 (28.6)