TABLE 2.
Fasting plasma concentrations of C-peptide in relation to total daily calcium intakes in healthy men and women12
| Q1 | Q2 | Q3 | Q4 | P-trend | |
|---|---|---|---|---|---|
| Men, n | 221 | 222 | 222 | 223 | |
| Median calcium intake, mg/d | 580 | 760 | 952 | 1408 | |
| C-peptide, μg/L | |||||
| Multivariate | 2.09 ± 0.16 | 1.94 ± 0.16 | 2.02 ± 0.15 | 1.95 ± 0.16 | 0.6 |
| Multivariate + BMI | 2.06 ± 0.16 | 1.91 ± 0.16 | 1.99 ± 0.15 | 1.92 ± 0.16 | 0.6 |
| Multivariate + BMI, vitamin D intake | 2.03 ± 0.16 | 1.88 ± 0.16 | 1.98 ± 0.15 | 1.89 ± 0.16 | 0.5 |
| Multivariate + BMI, vitamin D intake, dairy foods | 2.02 ± 0.11 | 1.89 ± 0.17 | 2.01 ± 0.15 | 1.88 ± 0.17 | 0.7 |
| Women,3n | 272 | 274 | 270 | 269 | |
| Median calcium intake, mg/d | 548 | 768 | 1103 | 1675 | |
| C-peptide, μg/L | |||||
| Multivariate | 2.01 ± 0.07 | 1.95 ± 0.07 | 1.83 ± 0.07 | 1.85 ± 0.07 | 0.01 |
| Multivariate + BMI | 1.98 ± 0.07 | 1.94 ± 0.06 | 1.84 ± 0.06 | 1.86. ± 0.06 | 0.03 |
| Multivariate + BMI, vitamin D intake | 1.98 ± 0.06 | 1.93 ± 0.06 | 1.84 ± 0.06 | 1.87 ± 0.06 | 0.03 |
| Multivariate + BMI, vitamin D intake, dairy foods | 1.97 ± 0.07 | 1.93 ± 0.01 | 1.84 ± 0.06 | 1.87 ± 0.06 | 0.05 |
1
Values are means ± SEM.
2
Other variables adjusted in the model include: age, smoking, physical activity, race, state of residence, hours of fasting, laboratory batch, time of blood draw, caffeinated and decaffeinated coffee consumption, alcohol, cereal fiber, retinol, and glycemic load intake, and total energy intake.
3
For women, we additionally adjusted for postmenopausal status and hormone use.