Table 3.
Global oxygen transport variables and acid-base balance of study patients
| Baseline | 12 hours | P value | |
| Oxygen delivery index (ml/min/m2) | 0.951 | ||
| Phenylephrine | 500 ± 205 | 498 ± 177 | |
| Norepinephrine | 499 ± 139 | 506 ± 140 | |
| Oxygen consumption index (ml/min/m2) | 0.568 | ||
| Phenylephrine | 164 ± 48 | 150 ± 41 | |
| Norepinephrine | 173 ± 53 | 161 ± 58 | |
| Oxygen extraction ratio (%) | 0.816 | ||
| Phenylephrine | 34 ± 9 | 32 ± 8 | |
| Norepinephrine | 36 ± 11 | 32 ± 10* | |
| Hemoglobin (g/dl) | 0.699 | ||
| Phenylephrine | 8.4 ± 0.9 | 8.4 ± 1.1 | |
| Norepinephrine | 8.3 ± 0.7 | 8.4 ± 0.6 | |
| pHa (-log10c(H+)) | 0.435 | ||
| Phenylephrine | 7.37 ± 0.07 | 7.37 ± 0.08 | |
| Norepinephrine | 7.35 ± 0.09 | 7.34 ± 0.08 | |
| Arterial base excess (mmol/l) | 0.228 | ||
| Phenylephrine | -0.2 ± 5.8 | 0.2 ± 6.3 | |
| Norepinephrine | -2.4 ± 6.6 | -3.0 ± 6.4 | |
| Arterial carbon dioxide partial pressure (mmHg) | 0.346 | ||
| Phenylephrine | 44 ± 10 | 44 ± 10 | |
| Norepinephrine | 41 ± 6 | 41 ± 6 | |
| Arterial oxygen partial pressure (mmHg) | 0.963 | ||
| Phenylephrine | 128 ± 36 | 119 ± 31 | |
| Norepinephrine | 121 ± 24 | 120 ± 26 | |
| Arterial oxygen saturation (%) | 0.912 | ||
| Phenylephrine | 98 ± 2 | 98 ± 2 | |
| Norepinephrine | 98 ± 1 | 98 ± 2 | |
| Mixed venous oxygen saturation (%) | 0.431 | ||
| Phenylephrine | 66 ± 9 | 67 ± 9 | |
| Norepinephrine | 64 ± 11 | 67 ± 10 | |
| PaO2/FiO2 | 0.971 | ||
| Phenylephrine | 229 ± 103 | 208 ± 89 | |
| Norepinephrine | 222 ± 75 | 218 ± 71 |
PaO2/FiO2, ratio of arterial oxygen partial pressure and inspiratory oxygen fraction (Horovitz index). *P < 0.05 versus baseline (significant time effect).