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. 2008 Dec 17;12(6):R161. doi: 10.1186/cc7160

Table 3.

Performance at admission or a fixed time thereafter.

Admission SOFA AUC Brier H/C-statistics Compared with AUC Brier H/C-statistics Mort.
Ho et al (2007) [11] 0.791 0.1 C = 7.97 APACHE II 0.858 0.09 H
p = 0.437 APS 0.829 0.09 C = 2.9 p = 0.890 H
RPHICU 0.822 0.09 C = 4.7 p = 0.198 H
Holtfreter et al (2006) [12] 0.72 APACHE II 0.785 H
Zygun et al (2005) [14] 0.67 U = 8.8 MODS 0.62 H/C = 10.28 H
p = 0.38 p = 0.17
Timsit et al (2002) [15] 0.72 U = 4.55 LODS 0.726 H/C = 10.4 H
p = 0.8 p = 0.16
Pettilä et al (2002) [17] 0.776 APACHE III 0.825 H
LODS 0.805 H
MODS 0.695 H
Khwannimit (2007) [10] 0.8786 LODS 0.8802 H
MODS 0.8606
Gosling et al (2006) [13] 0.61 APACHE II 0.62 I
Zygun et al (2005) [14] 0.67 U = 11.66 MODS 0.63 H/C = 14.29 I
p = 0.17 p = 0.05
Moreno et al (1999) [21] 0.772 I
Bota et al (2002) [16] 0.872 APACHE II 0.88 U
MODS 0.856 U
Ferreira et al (2001) [19] 0.79 I
Janssens et al (2000) [20] 0.82 SAPS II 0.77 H

Other scoring moments AUC Brier H/C-statistics Compared to AUC Brier H/C-statistics Mort.

Bota et al (2002) [16] 48 hours 0.844 MODS 0.834 U
Ferreira et al (2001) [19] 48 hours 0.78 I
Bota et al (2002) [16] 96 hours 0.847 MODS 0.861 U
Ferreira et al (2001) [19] 96 hours 0.82 I
Timsit et al (2002) [15], day 2 0.742 U = 11.1 LODS 0.742 H
p = 0.2
Timsit et al (2002) [15], day 3 0.762 U = 9.94 LODS 0.762 H
p = 0.27
Timsit et al (2002) [15], day 4 0.766 U = 10.5 LODS 0.766 H
p = 0.23
Timsit et al (2002) [15], day 5 0.746 U = 13.6 LODS 0.746 H
p = 0.09
Pettilä et al (2002) [17], day 5 0.727 LODS 0.76 H
H MODS 0.744
Timsit et al (2002) [15], day 6 0.763 U = 12.2 LODS 0.763 H
p = 0.14
Timsit et al (2002) [15], day 7 0.746 LODS 0.764 H
Bota et al (2002) [16], final 0.897 MODS 0.869 H

APACHE = Acute Physiology and Chronic Health Evaluation, APS = Acute Physiology Score (APACHE without chronic health and age condition), AUC = Area Under the Receiver Operating Characteristic Curve, H = Hospital, H/C = H- or C- Hosmer-Lemeshow statistics, I = Intensive care unit, LODS = Logistic Organ Dysfunction System, MODS = Multiple Organ Dysfunction Score, Mort. = Mortality, RPHICU = Royal Perth Hospital Intensive Care Unit, SAPS = Simplified Acute Physiology Score, SOFA = Sequential Organ Failure Assessment, U = Unspecified (mortality type or H/C statistic).