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. 2008 Dec 10;12(6):237. doi: 10.1186/cc7092

Table 1.

Definition of classes and levels of evidence used in AHA recommendations

Class I Conditions for which there is evidence for and/or general agreement that the procedure or treatment is useful and effective
Class II Conditions for which there is conflicting evidence and/or a divergence of opinion about the usefulness/efficacy of a procedure or treatment
Class IIa Weight of evidence or opinion is in favor of the procedure or treatment
Class IIb Usefulness/efficacy is less well established by evidence or opinion
Class III Conditions for which there is evidence and/or general agreement that the procedure or treatment is not useful/effective and in some cases may be harmful
Level of Evidence A Data derived from multiple randomized trials
Level of Evidence B Data derived from a single randomized trial or non-randomized trials
Level of Evidence C Expert Opinion or case studies

From [10].