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. 2008 Nov 4;12(6):R135. doi: 10.1186/cc7108

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Copyright © 2008 Varelmann et al.; licensee BioMed Central Ltd.

This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Density distributions. Density histograms taken from end-expiratory spiral computed tomography of all animals show normalized lung volume in Hounsfield units (HU) ranging from -1,000 to 100 plotted as mean ± standard error of the mean. Aeration categories (hyperinflated, normally aerated, poorly aerated, and non-aerated) are marked and were statistically compared (see Results and Discussion sections of the text for details) between pressure-controlled ventilation with (PCV + SB) and without (PCV – SB) spontaneous breathing. There were no significant differences caused by the type of acute lung injury. HCl-ALI, hydrochloric acid-induced acute lung injury; n/s, not significant; OA-A.