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. Author manuscript; available in PMC: 2010 Jan 1.
Published in final edited form as: Cell Immunol. 2008 Aug 30;254(2):105–109. doi: 10.1016/j.cellimm.2008.07.004

Figure 2. Immunosuppressive drugs inhibit lytic granule exocytosis in NK-92 cells.

Figure 2

Cells were pre-treated with the indicated concentration of CsA or FK 506 for 30 min and then stimulated with TG and PMA in the presence of the drugs. LAMP externalization assays were used to monitor granule exocytosis. A) Representative histograms of LAMP fluorescence for the different conditions. B) Quantifications for three such experiments. Data values that differ from the stimulated condition at p < 0.05 is indicated by *.