Figure 3. Re-introduction of one wild-type allele of p107 rescues the TKO myeloproliferative phenotype.
A Cytospins on unfractioned BM from control and Mx1-Cre p107-Single mice show a similar cellular composition 6 months after pI-pC treatment. B FACS analysis of BM progenitor cells in control (CT) and p107-Single mice. CāD Analysis of mature myeloid (Mac-1/Gr-1) and B cell (B220) populations in the BM (C) and the spleen (D) of control and p107-Single mice. E Analysis of DNA content (PI) of control and p107-Single KLS cells (n=3 ā p value: ns).