TABLE 3.
STUDIES OF PHOTODYNAMIC THERAPY (PDT) WITH BPD/VERTEPORFIN (PREVIOUSLY PUBLISHED AND CURRENT STUDY)
| CATEGORY | STUDY DESCRIPTION | STUDY |
|---|---|---|
| Previous work, published | Bolus BPD-LDL PDT of CNV at standard and higher irradiance (150–600 mW/cm2) | Miller7. |
| Bolus liposomal BPD at 600 mW/cm2, varying other laser and dye parameters in normal choroid and CNV | Kramer8 | |
| Slow infusion liposomal BPD (PDT of CNV at 600 mW/cm2) | Husain9 | |
| Long-term effects of liposomal BPD at 600 mW/cm2 in choroid and CNV | Husain11 | |
| Repeated PDT of choroid and optic nerve with liposomal BPD infusion at 600 mW/cm2 | Reinke6 | |
| Angiography results | Gragoudas ES, Miller JW, Zografos L, eds. Photodynamic Therapy of Ocular Diseases. Philadelphia: Lippincott, Williams & Wilkins; 2004 | |
| Unpublished findings | BPD-LDL at higher irradiances in choroid and CNV | Miller 7 and Current study |
| Liposomal BPD using higher fluence, higher irradiances in choroid and CNV | Kramer 8, Husain 9, and Current study |
BPD, benzoporphyrin derivative; CNV, choroidal neovascularization; LDL, low-density lipoprotein.