FIGURE 3.

Left, Unresolved clinically significant radiation macular edema. Fundus photograph of the left eye of 25-year-old woman 7 years following 5040 cGy of radiation for treatment of nasopharyngeal rhabdomyosarcoma. Vision is 20/200. Exudates and photocoagulation scars surround the center of the macula, which is edematous. The macular edema was retreated with limited scatter burns through areas of capillary nonperfusion but not closer than 500 μm from the center of the macula. Middle, Early venous phase fluorescein angiography. The left eye angiogram shows capillary nonperfusion in the papillomacular bundle and hyperfluorescence of microaneurysms and telangiectatic vessels. Prior photocoagulation burns are round and hypofluorescent. Right, Late-phase fluorescein angiography. Fluorescein dye has leaked into the superotemporal macula.