TABLE 5.
FINDINGS FROM SECOND SWEDISH THALIDOMIDE STUDY (n = 30)
| CASE NO. | SEX | OCULAR MOTILITY | TEARING WHEN EATING | EMOTIONAL TEARING | 7TH NERVE PALSY | SCHIRMER TEST SCORES (MM, OD/OS)
|
COMMENTS/DEFORMITIES | ||
|---|---|---|---|---|---|---|---|---|---|
| INITIAL | 5 MIN AFTER EATING | ≥10-MM DIFFERENCE | |||||||
| 1 | M | DS OU | OU | Normal | 0 | 2/2 | 12/12 | OU | Hearing ↓, external ear, thumb |
| 2 | M | DS OU | 0 | Normal | 0 | 2/2 | 19/28 | OU | Left upper limb, thumbs |
| 3 | M | Comitant ET | OU | Normal | 0 | 22/35 | 35/30 | OD | Hearing ↓; upper limbs; lower limb thumbs |
| 4 | F | Normal | 0 | Normal | 0 | 7/28 | 23/14 | OD | Upper limbs, hands and thumbs |
| 5 | M | Normal | 0 | Normal | 0 | 5/5 | 5/5 | – | Right hand and thumb |
| 6 | F | Normal | 0 | Normal | 0 | 16/13 | 32/30 | OU | Thumbs; lower limbs, hands |
| 7 | M | Normal | 0 | Normal | R | 5/7 | 8/10 | – | Hands; acquired 7th nerve palsy |
| 8 | M | Normal | 0 | Normal | 0 | 34/16 | 24/20 | – | Upper limbs, thumbs |
| 9 | M | DS OU | OU | Absent OU | 0 | 27/20 | 35/26 | – | Thumb |
| 10 | M | DS OU | OU | Absent OU | R/L | 5/10 | 30/35 | OU | – |
| 11 | F | Normal | 0 | Normal | R/L | 5/18 | 12/17 | – | Acquired 7th nerve palsy left, upper limbs, hands, thumbs |
| 12 | M | Normal | 0 | Normal | 0 | 7/8 | 15/20 | OS | Choanal atresia; hand, thumb, upper limbs, hypoplasia |
| 13 | F | Normal | 0 | Normal | 0 | 18/22 | 19/20 | – | Double vagina, upper and lower limbs, severe hands, thumbs |
| 14 | F | Refused examination | |||||||
| 15 | F | DS OU | OD | Absent OU | 0 | 1/7 | 17/24 | OU | Right inner ear, upper limbs and thumbs |
| 16 | F | DS OU | OD | Normal | L | 15/25 | 24/31 | – | – |
| 17 | M | ↓ Abduction Normal OS Enucleated | 0 | Normal | 0 | 35/35 | 35/35 | – | ↓ Hearing, upper limbs, thumbs |
| 18 | M | OD | 0 | Normal | 0 | NA/28 | NA/16 | – | Upper limbs, thumbs |
| 19 | F | DS OU | OU | Absent OS | 0 | 8/2 | 23/16 | OU | External ears, cataract OD |
| 20 | M | Normal | 0 | Normal | 7/11 | 9/13 | – | Hands, thumbs | |
| 21 | F | Normal | 0 | Normal | 0 | 15/20 | 17/22 | – | Hands, thumb, missing uterus and vagina |
| 22 | M | Normal | 0 | Normal | 0 | 0/0 | 0/13 | OS | Thumb; kidney |
| 23 | M | Normal | 0 | Normal | 0 | 35/35 | 35/35 | – | Thumb |
| 24 | M | DS OU | OU | Absent OU | R | 5/5 | 35/35 | OU | ↓ Hearing, hands, thumb |
| 25 | F | DS OU | OD | Absent OD | R | 0/2 | 17/30 | OU | ↓ Hearing left ear |
| 26 | M | DS OU | 0 | Normal | 0 | 19/35 | 35/35 | OD | Craniosynostosis, hand, thumbs |
| 27 | M | Normal | 0 | Normal | 0 | 15/25 | 12/35 | – | Upper limbs, hands, thumbs, foot |
| 28 | M | Brown S | 0 | Normal | 0 | 35/25 | 21/35 | – | Nystagmus, upper limb, hand, thumbs |
| 29 | F | Normal | 0 | Normal | 0 | 27/29 | 25/34 | – | Hands |
| 30 | M | DS OU | OU | Absent OU | 0 | 8/13 | 15/17 | – | Upper limbs, hands, left foot, triphalangeal thumbs |
| 31 | F | Normal | 0 | Normal | 0 | 14/30 | 9/9 | – | Thumbs, foot |
| Total | |||||||||
| 19 M, 12 F, age 44–46 y DS = 11; ↓ abduction = 1; Brown S = 1; 1 comitant ET | 10 of 30 | 7 absent | 6 | ||||||
Brown S, Brown syndrome; DS, Duane syndrome; ET, esotropia; NA, not applicable. 0, no tearing when eating or no 7th nerve palsy; +, positive finding; ↓, decreased; –, <10-mm.