Fig. 5.

Relative expression of mRNA for cytosolic dsRNA sensors: RIG-I (A) and MDA-5 (B), and for ISGs: OAS-1 (C) and IFIT2 (D) in blood of heifers carrying control, TI, or PI fetuses, detected with qRT-PCR. Data are presented as means ± SE. *P < 0.05, **P < 0.01, ***P < 0.001. Please note the scale differences between top panel (A, B) and bottom panel (C, D) graphs. RIG-I, retinoic acid-induced gene I; MDA-5, melanoma differentiation-associated protein 5; OAS-1, 2′,5′-olygoadenylate synthetase 1; IFIT-2, IFN-induced protein with tetratricopeptide repeats; d, day.