Table 3.

Processes affected by changes in CXCR4 and TCR signaling in blood of heifers carrying PI fetuses, day 160

Processes Affected by Changes in CXCR4 Signaling	%	P Value
Ras protein signal transduction	15.38	1.62E-07
Integrin-mediated signaling pathway	12.82	6.98E-07
Cell motility	17.95	7.76E-06
Signal complex formation	7.69	1.40E-05
T cell proliferation	7.69	2.43E-05
Protein amino acid phosphorylation	23.08	2.87E-05
Intracellular signaling cascade	15.38	2.88E-05
T cell differentiation	7.69	5.77E-05
Nerve growth factor receptor signaling pathway	5.13	8.20E-05
Protein kinase cascade	12.82	1.04E-04

Processes Affected by Changes in TCR Signaling	%	P Value
Positive regulation of T cell activation	13.79	4.53E-30
TCR signaling pathway	14.66	7.95E-27
Regulation of TCR signaling pathway	7.76	3.58E-19
Activation of NF-κB transcription factor	13.79	7.37E-19
T cell differentiation	10.34	2.25E-16
Intracellular signaling cascade	24.14	3.16E-14
Positive regulation of calcium-mediated signaling	7.76	1.63E-13
Ras protein signal transduction	10.34	1.02E-12
I-κB kinase/NF-κB cascade	7.76	1.55E-10
Response to molecule of bacterial origin	5.17	2.43E-10
Regulation of cell cycle	12.93	2.43E-10
Positive regulation of T cell proliferation	6.90	1.15E-08
Cell surface receptor-linked signal transduction	12.93	4.03E-08
Cellular defense response	7.76	8.21E-08
Immune response	15.52	1.55E-05
Protein modification process	7.76	1.69E-05
MAPK kinase cascade	5.17	5.20E-05
Caspase activation	5.17	8.77E-05

TCR, T cell receptor.