Fig 1.
Vasoreactivity of human skeletal muscle arterioles to the IK/SK channel activator, NS309. A, Dose-dependent relaxation of human skeletal muscle arterioles (n = 8) in response to NS309 pre- and post-CPB. *P < .05. B, Dose-dependent, NS309-mediated relaxation of pre-CPB human skeletal muscle arterioles pretreated in the absence or presence of TRAM34 and apamin (n = 6). **P < .001. C, Dose-dependent, NS309-mediated relaxation of pre-CPB human skeletal muscle arterioles (n = 6) with intact or denuded endothelium. **P < .001. Data are presented as percent relaxation after preconstriction with U46619.