Table 2.
Phenotypic, genetic, and environmental correlation of serum uric acid with circulating levels of CVD risk factors in the SAFHS
| Phenotype | h2 | rhoG | rhoE | rhoP |
|---|---|---|---|---|
| BMI | 0.547 (0.07)a | 0.204 (0.14) | 0.341 (0.09)a | 0.27a |
| Waist circumference (cm) | 0.541 (0.08)a | 0.280 (0.13)b | 0.286 (0.09)a | 0.28a |
| Total body fat (g) | 0.618 (0.08)a | 0.294 (0.13)b | 0.035 (0.10) | 0.17b |
| Waist-hip ratio | 0.348 (0.09)a | 0.289 (0.17) | 0.157 (0.08)c | 0.20b |
| Glucose (mg/dl) | 0.320 (0.07)a | 0.103 (0.18) | −0.10 (0.08) | NS |
| Insulin (μIU/ml) | 0.458 (0.09)a | 0.148 (0.16) | 0.235 (0.08)a | 0.20b |
| Triglycerides (mg/dl) | 0.535 (0.08)a | 0.184 (0.14) | 0.234 (0.09)b | 0.21a |
| HDL cholesterol (mg/dl) | 0.315 (0.07)a | −0.158 (0.17) | −0.13 (0.07)c | −0.18b |
| Total cholesterol (mg/dl) | 0.445 (0.08)a | 0.007 (0.15) | 0.064 (0.09) | NS |
| Systolic blood pressure (mm Hg) | 0.280 (0.08)a | 0.332 (0.21) | −0.05 (0.08) | 0.08c |
| Diastolic blood pressure (mm Hg) | 0.218 (0.07)a | 0.233 (0.21) | 0.01 (0.07) | NS |
| CRP (ng/ml) | 0.222 (0.15)a | −0.09 (0.44) | 0.495 (0.15)a | 0.31a |
| GM-CSF (pg/ml) | 0.327 (0.17)a | −0.18 (0.39) | 0.404 (0.23)c | 0.19b |
Data in parentheses represent se. h2, Heritability; rhoG, genetic correlation; rhoE, environmental correlation; rhoP, phenotypic correlation; NS, not significant.
P < 0.005.
P < 0.05.
P < 0.07.