Fig. 7.
Chlordecone reduces hepatic cholesteryl ester content. Animals were treated with corn oil, or 15 mg CD/kg (15 CD) body weight by ip injection. Liver was collected from individual animals (5–6 mice in each group) after 3 days. After lipid extraction with hexane, liver total (TC) and free CH (FC) content were determined using an enzymatic method as in Materials and methods. Hepatic esterified CH (CH-E) content was taken as the difference between the total CH and free CH. Values were expressed as mean CH level±SE. A statistically significant difference from the control was indicated by an asterisk.