Table 1. Mutational Frequencies of G[8,5-Me]T and T[5-Me,8]G Cross-Links in 293T and COS-7 Cells.

	G^T in 293T	T^G in 293T	G^T in COS-7	T^G in COS-7
targeted at G	4.6 ± 0.6	14.3 ± 3.6	3.7 ± 1.9	10.6 ± 5.4
targeted at T	1.2 ± 0.2	2.0 ± 0.9	1.0 ± 0.6	0.7 ± 0.02
semitargeted 5′ to the cross-link	5.4 ± 1.4	11.7 ± 2.1	4.4 ± 2.8	7.0 ± 0.7
semitargeted 3′ to the cross-link	4.6 ± 0.7	4.1 ± 1.9	9.1 ± 2.2	2.6 ± 1.5
frameshift	4.6 ± 0.7	3.6 ± 1.7	4.4 ± 0.9	2.9 ± 1.1
multiple substitutions	2.7 ± 0.06	2.0 ± 0.5	1.3 ± 0.8	0.7 ± 0.02