Figure 1.

Schematic diagram illustrating the approach used to synthesize paramagnetic porous polymersomes. (a) Vesicles consisting of the diblock copolymer PBdEO and the phospholipid POPC at a molar ratio of 85:15 were prepared. Second-generation dendrimer conjugated Gd chelates were encapsulated within the aqueous interior during vesicle formation. (b) Cross-linking of PBdEO within the vesicle bilayer was induced by free radical polymerization. (c) Pores were formed in the polymersome bilayer by extracting the POPC with the surfactant Triton X-100.