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. Author manuscript; available in PMC: 2009 Dec 1.
Published in final edited form as: Biochim Biophys Acta. 2008 Aug 27;1784(12):1873–1898. doi: 10.1016/j.bbapap.2008.08.012

Figure 8.

Figure 8

A. Structure of MeTr. Methyl-H4folate and base-off cobalamin were modeled into the active site of MeTr, with the methyl group of methyl-H4folate shown in green. From Fig. 5, [172]. B. The active site cavity of MeTr, based on the structure of the MeTr-methyl-H4folate binding site. From Fig. 5, [173]. C. Hydrogen bonding network near the N-5 of methyl-H4folate in the crystal structure of the binary complex of MeTr with methyl-H4folate [173].