Fig. 9.

Line graph depicts the time-related effects of iodoacetate + 2,4-dinitrophenol (50 μM) on renal venous secretion rate of 2′,3′-cAMP and 3′,5′-cAMP in kidneys obtained from four SHRs and two WKY rats. The effects of iodoacetate + 2,4-dinitrophenol were independent of strain, so the results from all six kidneys were combined. Data are shown as percentage of time 0 (basal) levels of 2′,3′-cAMP and 3′,5′-cAMP at the indicated time after administration of iodoacetate + 2,4-dinitrophenol. Statistical analysis is from two-factor analysis of variance.